P2.03b-089 CD1C in Lung Adenocarcinoma: Prognosis and Cellular Origin
نویسندگان
چکیده
منابع مشابه
RB and Prognosis in Resected Lung Adenocarcinoma.
The treatment of resected lung adenocarcinoma has ample room for improvement. Can genomic characterization aid us in deciding how and when to apply adjuvant therapy in the smallest resected tumors?
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PURPOSE Adenocarcinoma, the most common non-small cell lung cancer is a leading cause of death worldwide, with a low overall survival (OS) despite increasing attempts to achieve an early diagnosis and accomplish surgical and multimodality treatment strategies. Cellular retinol binding protein-1 (CRBP-1) regulates retinol bioavailability and cell differentiation, but its role in lung cancerogene...
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Fibroblast growth factor 19 (FGF19) belong to the FGF19 subfamily which is widely distributed in human tissues. FGF19 plays a crucial role in regulating various cellular processes. Recently, the researchers found that the aberrant expression of FGF19 in tumor development and progression. However, to our limited knowledge, whether FGF19 functions in lung adenocarcinoma remains unknown. In our re...
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Pancreatic cancer has a very poor prognosis, in part due to its diagnosis at late stages of the disease and to limited response to chemotherapy and radiotherapy. The vast majority of pancreatic cancers are classified as pancreatic ductal adenocarcinomas (PDACs). Despite advances in knowledge on the cellular origin of PDAC or the involvement of signal transduction pathways therein, many question...
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BACKGROUND This study was conducted to investigate the clinical significance of claudin-1 (CLDN1) expression in patients with lung adenocarcinoma. METHODS We examined CLDN1 protein expression by immunohistochemistry in a tissue microarray from 258 patients with lung adenocarcinoma. We investigated messenger ribonucleic acid (mRNA) expression in H358 (formerly bronchioloalveolar carcinoma) and...
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ژورنال
عنوان ژورنال: Journal of Thoracic Oncology
سال: 2017
ISSN: 1556-0864
DOI: 10.1016/j.jtho.2016.11.1371